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Conversion of Methylglyoxal to Acetol by Escherichia coli Aldo-Keto Reductases

Methylglyoxal (MG) is a toxic metabolite known to accumulate in various cell types. We detected in vivo conversion of MG to acetol in MG-accumulating Escherichia coli cells by use of (1)H nuclear magnetic resonance ((1)H-NMR) spectroscopy. A search for homologs of the mammalian aldo-keto reductases...

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Detalhes bibliográficos
Main Authors: Ko, Junsang, Kim, Insook, Yoo, Seokho, Min, Bumchan, Kim, Kyungmin, Park, Chankyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1196063/
https://ncbi.nlm.nih.gov/pubmed/16077126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.16.5782-5789.2005
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