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Conversion of Methylglyoxal to Acetol by Escherichia coli Aldo-Keto Reductases
Methylglyoxal (MG) is a toxic metabolite known to accumulate in various cell types. We detected in vivo conversion of MG to acetol in MG-accumulating Escherichia coli cells by use of (1)H nuclear magnetic resonance ((1)H-NMR) spectroscopy. A search for homologs of the mammalian aldo-keto reductases...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2005
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1196063/ https://ncbi.nlm.nih.gov/pubmed/16077126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.16.5782-5789.2005 |
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