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A comparative study of methylglyoxal metabolism in trypanosomatids

The glyoxalase system, comprising the metalloenzymes glyoxalase I (GLO1) and glyoxalase II (GLO2), is an almost universal metabolic pathway involved in the detoxification of the glycolytic byproduct methylglyoxal to d-lactate. In contrast to the situation with the trypanosomatid parasites Leishmania...

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Detalhes bibliográficos
Main Authors: Greig, Neil, Wyllie, Susan, Patterson, Stephen, Fairlamb, Alan H
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2702497/
https://ncbi.nlm.nih.gov/pubmed/19076214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2008.06788.x
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