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Methylglyoxal metabolism in trypanosomes and leishmania
Methylglyoxal is a toxic by-product of glycolysis and other metabolic pathways. In mammalian cells, the principal route for detoxification of this reactive metabolite is via the glutathione-dependent glyoxalase pathway forming d-lactate, involving lactoylglutathione lyase (GLO1; EC 4.4.1.5) and hydr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Academic Press
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107426/ https://ncbi.nlm.nih.gov/pubmed/21310261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2011.02.001 |
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