Chitinase 3-like 1-CD44 interaction promotes metastasis and epithelial-to-mesenchymal transition through β-catenin/Erk/Akt signaling in gastric cancer

BACKGROUND: Enzymatically inactive chitinase-like protein CHI3L1 drives inflammatory response and promotes tumor progression. However, its role in gastric cancer (GC) tumorigenesis and metastasis has not yet been fully elucidated. We determined the significance of CHI3L1 expression in patients with...

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Dades bibliogràfiques
Publicat a:J Exp Clin Cancer Res
Autors principals: Geng, Biao, Pan, Jinshun, Zhao, Ting, Ji, Jie, Zhang, Chen, Che, Ying, Yang, Jing, Shi, Hui, Li, Juan, Zhou, Hong, Mu, Xianmin, Xu, Che, Wang, Chao, Xu, Yue, Liu, Zheng, Wen, Hao, You, Qiang
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6117920/
https://ncbi.nlm.nih.gov/pubmed/30165890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0876-2
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