CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasis

BACKGROUND: Pancreatic cancer is a lethal disease due to the high incidence of metastasis at the time of detection. CD133 expression in clinical pancreatic cancer correlates with poor prognosis and metastasis. However, the molecular mechanism of CD133-regulated metastasis remains unclear. In recent...

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Bibliographic Details
Main Authors: Ding, Qiang, Miyazaki, Yumi, Tsukasa, Koichiro, Matsubara, Shyuichiro, Yoshimitsu, Makoto, Takao, Sonshin
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931313/
https://ncbi.nlm.nih.gov/pubmed/24468059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-15
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