CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasis

BACKGROUND: Pancreatic cancer is a lethal disease due to the high incidence of metastasis at the time of detection. CD133 expression in clinical pancreatic cancer correlates with poor prognosis and metastasis. However, the molecular mechanism of CD133-regulated metastasis remains unclear. In recent...

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Hauptverfasser: Ding, Qiang, Miyazaki, Yumi, Tsukasa, Koichiro, Matsubara, Shyuichiro, Yoshimitsu, Makoto, Takao, Sonshin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931313/
https://ncbi.nlm.nih.gov/pubmed/24468059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-15
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