CD133 Modulate HIF-1α Expression under Hypoxia in EMT Phenotype Pancreatic Cancer Stem-Like Cells

Although CD133 is a known representative cancer stem cell marker, its function in tumor aggressiveness under hypoxia is not fully known. The aim of this study is to demonstrate that CD133 regulates hypoxia inducible factor (HIF)-1α expression with tumor migration. The CD133(+) pancreatic cancer cell...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Maeda, Koki, Ding, Qiang, Yoshimitsu, Makoto, Kuwahata, Taisaku, Miyazaki, Yumi, Tsukasa, Koichirou, Hayashi, Tomomi, Shinchi, Hiroyuki, Natsugoe, Shoji, Takao, Sonshin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964401/
https://ncbi.nlm.nih.gov/pubmed/27367674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17071025
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