CD133 Modulate HIF-1α Expression under Hypoxia in EMT Phenotype Pancreatic Cancer Stem-Like Cells

Although CD133 is a known representative cancer stem cell marker, its function in tumor aggressiveness under hypoxia is not fully known. The aim of this study is to demonstrate that CD133 regulates hypoxia inducible factor (HIF)-1α expression with tumor migration. The CD133(+) pancreatic cancer cell...

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Pubblicato in:Int J Mol Sci
Autori principali: Maeda, Koki, Ding, Qiang, Yoshimitsu, Makoto, Kuwahata, Taisaku, Miyazaki, Yumi, Tsukasa, Koichirou, Hayashi, Tomomi, Shinchi, Hiroyuki, Natsugoe, Shoji, Takao, Sonshin
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4964401/
https://ncbi.nlm.nih.gov/pubmed/27367674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17071025
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