CD133 facilitates epithelial-mesenchymal transition through interaction with the ERK pathway in pancreatic cancer metastasis

BACKGROUND: Pancreatic cancer is a lethal disease due to the high incidence of metastasis at the time of detection. CD133 expression in clinical pancreatic cancer correlates with poor prognosis and metastasis. However, the molecular mechanism of CD133-regulated metastasis remains unclear. In recent...

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Autors principals: Ding, Qiang, Miyazaki, Yumi, Tsukasa, Koichiro, Matsubara, Shyuichiro, Yoshimitsu, Makoto, Takao, Sonshin
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3931313/
https://ncbi.nlm.nih.gov/pubmed/24468059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-15
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