MicroRNA-7 Inhibits Tumor Metastasis and Reverses Epithelial-Mesenchymal Transition through AKT/ERK1/2 Inactivation by Targeting EGFR in Epithelial Ovarian Cancer

Epidermal growth factor receptor (EGFR) overexpression and activation result in increased proliferation and migration of solid tumors including ovarian cancer. In recent years, mounting evidence indicates that EGFR is a direct and functional target of miR-7. In this study, we found that miR-7 expres...

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Dettagli Bibliografici
Autori principali: Zhou, Xingchen, Hu, Yuan, Dai, Lan, Wang, Yunfei, Zhou, Jinhua, Wang, WenWen, Di, Wen, Qiu, Lihua
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4016102/
https://ncbi.nlm.nih.gov/pubmed/24816687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096718
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