Plasma AR and abiraterone-resistant prostate cancer

AR gene aberrations are rare in prostate cancer prior to primary hormone treatment but emerge with castration resistance. To determine AR gene status using a minimally-invasive assay that could have broad clinical utility, we developed a targeted next-generation sequencing approach amenable to plasm...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Romanel, Alessandro, Gasi Tandefelt, Delila, Conteduca, Vincenza, Jayaram, Anuradha, Casiraghi, Nicola, Wetterskog, Daniel, Salvi, Samanta, Amadori, Dino, Zafeiriou, Zafeiris, Rescigno, Pasquale, Bianchini, Diletta, Gurioli, Giorgia, Casadio, Valentina, Carreira, Suzanne, Goodall, Jane, Wingate, Anna, Ferraldeschi, Roberta, Tunariu, Nina, Flohr, Penny, De Giorgi, Ugo, de Bono, Johann S, Demichelis, Francesca, Attard, Gerhardt
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112410/
https://ncbi.nlm.nih.gov/pubmed/26537258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac9511
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