Plasma AR and abiraterone-resistant prostate cancer

AR gene aberrations are rare in prostate cancer prior to primary hormone treatment but emerge with castration resistance. To determine AR gene status using a minimally-invasive assay that could have broad clinical utility, we developed a targeted next-generation sequencing approach amenable to plasm...

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Publié dans:Sci Transl Med
Auteurs principaux: Romanel, Alessandro, Gasi Tandefelt, Delila, Conteduca, Vincenza, Jayaram, Anuradha, Casiraghi, Nicola, Wetterskog, Daniel, Salvi, Samanta, Amadori, Dino, Zafeiriou, Zafeiris, Rescigno, Pasquale, Bianchini, Diletta, Gurioli, Giorgia, Casadio, Valentina, Carreira, Suzanne, Goodall, Jane, Wingate, Anna, Ferraldeschi, Roberta, Tunariu, Nina, Flohr, Penny, De Giorgi, Ugo, de Bono, Johann S, Demichelis, Francesca, Attard, Gerhardt
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6112410/
https://ncbi.nlm.nih.gov/pubmed/26537258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aac9511
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