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Chronic Activation of Liver X Receptor Sensitizes Mice to High Cholesterol Diet–Induced Gut Toxicity
Cholesterol is essential for numerous biologic functions and processes, but an excess of intracellular cholesterol can be toxic. Intestinal cholesterol absorption is a major determinant of plasma cholesterol level. The liver X receptor (LXR) is a nuclear receptor known for its activity in cholestero...
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| Publicado no: | Mol Pharmacol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6108576/ https://ncbi.nlm.nih.gov/pubmed/30045953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.112672 |
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