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Regulation of Cholesterol Sulfotransferase SULT2B1b by Hepatocyte Nuclear Factor 4α Constitutes a Negative Feedback Control of Hepatic Gluconeogenesis

The cholesterol sulfotransferase SULT2B1b converts cholesterol to cholesterol sulfate (CS). We previously reported that SULT2B1b inhibits hepatic gluconeogenesis by antagonizing the gluconeogenic activity of hepatocyte nuclear factor 4α (HNF4α). In this study, we showed that the SULT2B1b gene is a t...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Bi, Yuhan, Shi, Xiongjie, Zhu, Junjie, Guan, Xiudong, Garbacz, Wojciech G., Huang, Yixian, Gao, Li, Yan, Jiong, Xu, Meishu, Ren, Songrong, Ren, Shunlin, Liu, Yulan, Ma, Xiaochao, Li, Song, Xie, Wen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854833/
https://ncbi.nlm.nih.gov/pubmed/29378829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00654-17
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