Regulation of Cholesterol Sulfotransferase SULT2B1b by Hepatocyte Nuclear Factor 4α Constitutes a Negative Feedback Control of Hepatic Gluconeogenesis

The cholesterol sulfotransferase SULT2B1b converts cholesterol to cholesterol sulfate (CS). We previously reported that SULT2B1b inhibits hepatic gluconeogenesis by antagonizing the gluconeogenic activity of hepatocyte nuclear factor 4α (HNF4α). In this study, we showed that the SULT2B1b gene is a t...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Bi, Yuhan, Shi, Xiongjie, Zhu, Junjie, Guan, Xiudong, Garbacz, Wojciech G., Huang, Yixian, Gao, Li, Yan, Jiong, Xu, Meishu, Ren, Songrong, Ren, Shunlin, Liu, Yulan, Ma, Xiaochao, Li, Song, Xie, Wen
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854833/
https://ncbi.nlm.nih.gov/pubmed/29378829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00654-17
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