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An Unexpected Role of Cholesterol Sulfotransferase and its Regulation in Sensitizing Mice to Acetaminophen-Induced Liver Injury
Overdose of acetaminophen (APAP) is the leading cause of acute liver failure (ALF) in the United States. The sulfotransferase-mediated sulfation of APAP is widely believed to be a protective mechanism to attenuate the hepatotoxicity of APAP. The cholesterol sulfotransferase SULT2B1b is best known fo...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Pharmacol |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The American Society for Pharmacology and Experimental Therapeutics
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6491915/ https://ncbi.nlm.nih.gov/pubmed/30944208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.118.114819 |
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