Fatostatin induces pro- and anti-apoptotic lipid accumulation in breast cancer

Given the dependence of cancers on de novo lipogenesis, we tested the effect of fatostatin, a small molecule thought to target this pathway by blocking activation of SREBP transcription factors, in breast cancer cell lines and xenograft tumors. We found that estrogen receptor (ER) positive cells wer...

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Xehetasun bibliografikoak
Argitaratua izan da:Oncogenesis
Egile Nagusiak: Brovkovych, Viktor, Izhar, Yasir, Danes, Jeanne M., Dubrovskyi, Oleskii, Sakallioglu, Isin T., Morrow, Lauren M., Atilla-Gokcumen, G. Ekin, Frasor, Jonna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107643/
https://ncbi.nlm.nih.gov/pubmed/30140005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0076-0
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