EspH is a hypervirulence factor for Mycobacterium marinum and essential for the secretion of the ESX-1 substrates EspE and EspF

The pathogen Mycobacterium tuberculosis employs a range of ESX-1 substrates to manipulate the host and build a successful infection. Although the importance of ESX-1 secretion in virulence is well established, the characterization of its individual components and the role of individual substrates is...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Phan, Trang H., van Leeuwen, Lisanne M., Kuijl, Coen, Ummels, Roy, van Stempvoort, Gunny, Rubio-Canalejas, Alba, Piersma, Sander R., Jiménez, Connie R., van der Sar, Astrid M., Houben, Edith N. G., Bitter, Wilbert
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6107294/
https://ncbi.nlm.nih.gov/pubmed/30102741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007247
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