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EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis
The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we show that EspL, a protein of 115 amino acids, is essential for mediating E...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6319747/ https://ncbi.nlm.nih.gov/pubmed/30571761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007491 |
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