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Conserved ESX-1 Substrates EspE and EspF Are Virulence Factors That Regulate Gene Expression

Mycobacterium tuberculosis, the cause of human tuberculosis, and Mycobacterium marinum, a nontubercular pathogen with a broad host range, require the ESX-1 secretion system for virulence. The ESX-1 system secretes proteins which cause phagosomal lysis within the macrophage via an unknown mechanism....

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Chirakos, Alexandra E., Nicholson, Kathleen R., Huffman, Allison, Champion, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7671884/
https://ncbi.nlm.nih.gov/pubmed/32900815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00289-20
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