EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis

The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we show that EspL, a protein of 115 amino acids, is essential for mediating E...

Full description

Saved in:
Bibliographic Details
Published in:PLoS Pathog
Main Authors: Sala, Claudia, Odermatt, Nina T., Soler-Arnedo, Paloma, Gülen, Muhammet F., von Schultz, Sofia, Benjak, Andrej, Cole, Stewart T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6319747/
https://ncbi.nlm.nih.gov/pubmed/30571761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007491
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items