Modification of a PE/PPE substrate pair reroutes an Esx substrate pair from the mycobacterial ESX-1 type VII secretion system to the ESX-5 system

Bacterial type VII secretion systems secrete a wide range of extracellular proteins that play important roles in bacterial viability and in interactions of pathogenic mycobacteria with their hosts. Mycobacterial type VII secretion systems consist of five subtypes, ESX-1–5, and have four substrate cl...

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Vydáno v:J Biol Chem
Hlavní autoři: Damen, Merel P. M., Phan, Trang H., Ummels, Roy, Rubio-Canalejas, Alba, Bitter, Wilbert, Houben, Edith N. G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7196631/
https://ncbi.nlm.nih.gov/pubmed/32184351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011682
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