Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes

Pathogenic mycobacteria contain up to five type VII secretion (T7S) systems, ESX-1 to ESX-5. One of the conserved T7S components is the serine protease mycosin (MycP). Strikingly, whereas MycP is essential for secretion, the protease activity of MycP(1) in Mycobacterium tuberculosis has been shown t...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: van Winden, Vincent J. C., Ummels, Roy, Piersma, Sander R., Jiménez, Connie R., Korotkov, Konstantin V., Bitter, Wilbert, Houben, Edith N. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082899/
https://ncbi.nlm.nih.gov/pubmed/27795391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01471-16
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