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Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes

Pathogenic mycobacteria contain up to five type VII secretion (T7S) systems, ESX-1 to ESX-5. One of the conserved T7S components is the serine protease mycosin (MycP). Strikingly, whereas MycP is essential for secretion, the protease activity of MycP(1) in Mycobacterium tuberculosis has been shown t...

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發表在:mBio
Main Authors: van Winden, Vincent J. C., Ummels, Roy, Piersma, Sander R., Jiménez, Connie R., Korotkov, Konstantin V., Bitter, Wilbert, Houben, Edith N. G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082899/
https://ncbi.nlm.nih.gov/pubmed/27795391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01471-16
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