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Understanding specificity of the mycosin proteases in ESX/type VII secretion by structural and functional analysis

Mycobacteria use specialized ESX secretion systems to transport proteins across their cell membranes in order to manipulate their environment. In pathogenic Mycobacterium tuberculosis there are five paralogous ESX secretion systems, named ESX-1 through ESX-5. Each system includes a substilisin-like...

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Detalhes bibliográficos
Main Authors: Wagner, Jonathan M., Evans, Timothy J., Chen, Jing, Zhu, Haining, Houben, Edith N. G., Bitter, Wilbert, Korotkov, Konstantin V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859186/
https://ncbi.nlm.nih.gov/pubmed/24113528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.09.022
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