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Mycosins Are Required for the Stabilization of the ESX-1 and ESX-5 Type VII Secretion Membrane Complexes

Pathogenic mycobacteria contain up to five type VII secretion (T7S) systems, ESX-1 to ESX-5. One of the conserved T7S components is the serine protease mycosin (MycP). Strikingly, whereas MycP is essential for secretion, the protease activity of MycP(1) in Mycobacterium tuberculosis has been shown t...

詳細記述

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書誌詳細
出版年:mBio
主要な著者: van Winden, Vincent J. C., Ummels, Roy, Piersma, Sander R., Jiménez, Connie R., Korotkov, Konstantin V., Bitter, Wilbert, Houben, Edith N. G.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5082899/
https://ncbi.nlm.nih.gov/pubmed/27795391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01471-16
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