KRAS(G12D) and TP53(R167H) Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus scrofa Pigs

Although survival has improved in recent years, the prognosis of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remains poor. Despite substantial differences in anatomy, physiology, genetics, and metabolism, the overwhelming majority of preclinical testing relies on transgenic mice....

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Principe, Daniel R., Overgaard, Nana Haahr, Park, Alex J., Diaz, Andrew M., Torres, Carolina, McKinney, Ronald, Dorman, Matthew J., Castellanos, Karla, Schwind, Regina, Dawson, David W., Rana, Ajay, Maker, Ajay, Munshi, Hidayatullah G., Rund, Lauretta A., Grippo, Paul J., Schook, Lawrence B.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105629/
https://ncbi.nlm.nih.gov/pubmed/30135483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30916-6
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