KRAS(G12D) and TP53(R167H) Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus scrofa Pigs

Although survival has improved in recent years, the prognosis of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remains poor. Despite substantial differences in anatomy, physiology, genetics, and metabolism, the overwhelming majority of preclinical testing relies on transgenic mice....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Principe, Daniel R., Overgaard, Nana Haahr, Park, Alex J., Diaz, Andrew M., Torres, Carolina, McKinney, Ronald, Dorman, Matthew J., Castellanos, Karla, Schwind, Regina, Dawson, David W., Rana, Ajay, Maker, Ajay, Munshi, Hidayatullah G., Rund, Lauretta A., Grippo, Paul J., Schook, Lawrence B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105629/
https://ncbi.nlm.nih.gov/pubmed/30135483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30916-6
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