KRAS(G12D) and TP53(R167H) Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus scrofa Pigs

Although survival has improved in recent years, the prognosis of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remains poor. Despite substantial differences in anatomy, physiology, genetics, and metabolism, the overwhelming majority of preclinical testing relies on transgenic mice....

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Principe, Daniel R., Overgaard, Nana Haahr, Park, Alex J., Diaz, Andrew M., Torres, Carolina, McKinney, Ronald, Dorman, Matthew J., Castellanos, Karla, Schwind, Regina, Dawson, David W., Rana, Ajay, Maker, Ajay, Munshi, Hidayatullah G., Rund, Lauretta A., Grippo, Paul J., Schook, Lawrence B.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105629/
https://ncbi.nlm.nih.gov/pubmed/30135483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30916-6
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