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PIK3CA mutations and TP53 alterations cooperate to increase cancerous phenotypes and tumor heterogeneity
BACKGROUND/PURPOSE: The combined contributions of oncogenes and tumor suppressor genes toward carcino-genesis remain poorly understood. Elucidation of cancer gene cooperativity can provide new insights leading to more effective use of therapies. EXPERIMENTAL DESIGN/METHODS: We used somatic cell geno...
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| 出版年: | Breast Cancer Res Treat |
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| 主要な著者: | , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6100768/ https://ncbi.nlm.nih.gov/pubmed/28190247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4147-2 |
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