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ESR1 mutations in circulating plasma tumor DNA from metastatic breast cancer patients

PURPOSE: Mutations in the estrogen receptor-alpha (ER) gene, ESR1, have been identified in breast cancer metastases after progression on endocrine therapies. Due to limitations of metastatic biopsies, the reported frequency of ESR1 mutations may be underestimated. Here, we show a high frequency of E...

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出版年:Clin Cancer Res
主要な著者: Chu, David, Paoletti, Costanza, Gersch, Christina, VanDenBerg, Dustin A., Zabransky, Daniel J., Cochran, Rory L., Wong, Hong Yuen, Toro, Patricia Valda, Cidado, Justin, Croessmann, Sarah, Erlanger, Bracha, Cravero, Karen, Kyker-Snowman, Kelly, Button, Berry, Parsons, Heather, Dalton, W. Brian, Gillani, Riaz, Medford, Arielle, Aung, Kimberly, Tokudome, Nahomi, Chinnaiyan, Arul M., Schott, Anne, Robinson, Dan, Jacks, Karen S., Lauring, Josh, Hurley, Paula, Hayes, Daniel F., Rae, James, Park, Ben Ho
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993201/
https://ncbi.nlm.nih.gov/pubmed/26261103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0943
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