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DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme

Cancer cells can resist the effects of DNA-damaging therapeutic agents via utilization of DNA repair pathways, suggesting that DNA repair capacity (DRC) measurements in cancer cells could be used to identify patients most likely to respond to treatment. However, the limitations of available technolo...

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Publicat a:Cancer Res
Autors principals: Nagel, Zachary D., Kitange, Gaspar J., Gupta, Shiv K., Joughin, Brian A., Chaim, Isaac A., Mazzucato, Patrizia, Lauffenburger, Douglas A., Sarkaria, Jann N., Samson, Leona D.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6100738/
https://ncbi.nlm.nih.gov/pubmed/27793847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1151
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