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Chronic cannabis promotes pro-hallucinogenic signaling of 5-HT2A receptors through Akt/mTOR pathway

Long-term use of potent cannabis during adolescence increases the risk of developing schizophrenia later in life, but to date, the mechanisms involved remain unknown. Several findings suggest that the functional selectivity of serotonin 2A receptor (5-HT2AR) through inhibitory G-proteins is involved...

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Podrobná bibliografie
Vydáno v:Neuropsychopharmacology
Hlavní autoři: Ibarra-Lecue, Inés, Mollinedo-Gajate, Irene, Meana, J Javier, Callado, Luis F, Diez-Alarcia, Rebeca, Urigüen, Leyre
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer International Publishing 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098160/
https://ncbi.nlm.nih.gov/pubmed/29748632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0076-y
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