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Chronic cannabis promotes pro-hallucinogenic signaling of 5-HT2A receptors through Akt/mTOR pathway

Long-term use of potent cannabis during adolescence increases the risk of developing schizophrenia later in life, but to date, the mechanisms involved remain unknown. Several findings suggest that the functional selectivity of serotonin 2A receptor (5-HT2AR) through inhibitory G-proteins is involved...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Ibarra-Lecue, Inés, Mollinedo-Gajate, Irene, Meana, J Javier, Callado, Luis F, Diez-Alarcia, Rebeca, Urigüen, Leyre
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6098160/
https://ncbi.nlm.nih.gov/pubmed/29748632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0076-y
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