Murine Pneumonia Virus Expressing the Fusion Glycoprotein of Human Respiratory Syncytial Virus from an Added Gene Is Highly Attenuated and Immunogenic in Rhesus Macaques

Human respiratory syncytial virus (RSV) continues to be the leading viral cause of severe acute lower respiratory tract disease in infants and children worldwide. A licensed vaccine or antiviral drug suitable for routine use remains unavailable. Like RSV, Murine pneumonia virus (MPV) is a member of...

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Bibliographic Details
Published in:J Virol
Main Authors: Brock, Linda G., Liu, Xiang, Liang, Bo, Lingemann, Matthias, Liu, Xueqiao, Herbert, Richard, Hackenberg, Ashley D., Buchholz, Ursula J., Collins, Peter L., Munir, Shirin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096832/
https://ncbi.nlm.nih.gov/pubmed/29925656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00723-18
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