Chimeric Bovine/Human Parainfluenza Virus Type 3 Expressing Respiratory Syncytial Virus (RSV) F Glycoprotein: Effect of Insert Position on Expression, Replication, Immunogenicity, Stability, and Protection against RSV Infection

A recombinant chimeric bovine/human parainfluenza type 3 virus (rB/HPIV3) vector expressing the respiratory syncytial virus (RSV) fusion F glycoprotein previously exhibited disappointing levels of RSV F immunogenicity and genetic stability in children (D. Bernstein et al., Pediatr. Infect. Dis. J. 3...

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Bibliografiska uppgifter
Huvudupphovsmän: Liang, Bo, Munir, Shirin, Amaro-Carambot, Emerito, Surman, Sonja, Mackow, Natalie, Yang, Lijuan, Buchholz, Ursula J., Collins, Peter L., Schaap-Nutt, Anne
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993740/
https://ncbi.nlm.nih.gov/pubmed/24478424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03481-13
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