Effects of Alterations to the CX3C Motif and Secreted Form of Human Respiratory Syncytial Virus (RSV) G Protein on Immune Responses to a Parainfluenza Virus Vector Expressing the RSV G Protein

Human respiratory syncytial virus (RSV) is a major pediatric respiratory pathogen. The attachment (G) and fusion (F) glycoproteins are major neutralization and protective antigens. RSV G is expressed as membrane-anchored (mG) and -secreted (sG) forms, both containing a central fractalkine-like CX3C...

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Veröffentlicht in:J Virol
Hauptverfasser: Liang, Bo, Kabatova, Barbora, Kabat, Juraj, Dorward, David W., Liu, Xiang, Surman, Sonja, Liu, Xueqiao, Moseman, Annie Park, Buchholz, Ursula J., Collins, Peter L., Munir, Shirin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6430528/
https://ncbi.nlm.nih.gov/pubmed/30651356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02043-18
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