Attenuated Human Parainfluenza Virus Type 1 Expressing the Respiratory Syncytial Virus (RSV) Fusion (F) Glycoprotein from an Added Gene: Effects of Prefusion Stabilization and Packaging of RSV F

Human respiratory syncytial virus (RSV) is the most prevalent worldwide cause of severe respiratory tract infection in infants and young children. Human parainfluenza virus type 1 (HPIV1) also causes severe pediatric respiratory illness, especially croup. Both viruses lack vaccines. Here, we describ...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Liu, Xiang, Liang, Bo, Ngwuta, Joan, Liu, Xueqiao, Surman, Sonja, Lingemann, Matthias, Kwong, Peter D., Graham, Barney S., Collins, Peter L., Munir, Shirin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660469/
https://ncbi.nlm.nih.gov/pubmed/28835504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01101-17
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