Cerebrospinal fluid neurogranin concentration in neurodegeneration: relation to clinical phenotypes and neuropathology

Neurogranin (Ng) is a post-synaptic protein that previously has been shown to be a biomarker for synaptic function when measured in cerebrospinal fluid (CSF). The CSF concentration of Ng is increased in Alzheimer’s disease dementia (ADD), and even in the pre-dementia stage. In this prospective study...

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Détails bibliographiques
Publié dans:Acta Neuropathol
Auteurs principaux: Portelius, Erik, Olsson, Bob, Höglund, Kina, Cullen, Nicholas C., Kvartsberg, Hlin, Andreasson, Ulf, Zetterberg, Henrik, Sandelius, Åsa, Shaw, Leslie M., Lee, Virginia M. Y., Irwin, David J., Grossman, Murray, Weintraub, Daniel, Chen-Plotkin, Alice, Wolk, David A., McCluskey, Leo, Elman, Lauren, McBride, Jennifer, Toledo, Jon B., Trojanowski, John Q., Blennow, Kaj
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2018
Sujets:
Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096740/
https://ncbi.nlm.nih.gov/pubmed/29700597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-018-1851-x
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