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Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer’s disease

Synaptic dysfunction is linked to cognitive symptoms in Alzheimer’s disease. Thus, measurement of synapse proteins in cerebrospinal fluid may be useful biomarkers to monitor synaptic degeneration. Cerebrospinal fluid levels of the postsynaptic protein neurogranin are increased in Alzheimer’s disease...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Portelius, Erik, Zetterberg, Henrik, Skillbäck, Tobias, Törnqvist, Ulrika, Andreasson, Ulf, Trojanowski, John Q., Weiner, Michael W., Shaw, Leslie M., Mattsson, Niklas, Blennow, Kaj
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643642/
https://ncbi.nlm.nih.gov/pubmed/26373605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv267
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