Cerebrospinal fluid neurogranin: relation to cognition and neurodegeneration in Alzheimer’s disease

Synaptic dysfunction is linked to cognitive symptoms in Alzheimer’s disease. Thus, measurement of synapse proteins in cerebrospinal fluid may be useful biomarkers to monitor synaptic degeneration. Cerebrospinal fluid levels of the postsynaptic protein neurogranin are increased in Alzheimer’s disease...

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Detalles Bibliográficos
Publicado en:Brain
Main Authors: Portelius, Erik, Zetterberg, Henrik, Skillbäck, Tobias, Törnqvist, Ulrika, Andreasson, Ulf, Trojanowski, John Q., Weiner, Michael W., Shaw, Leslie M., Mattsson, Niklas, Blennow, Kaj
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643642/
https://ncbi.nlm.nih.gov/pubmed/26373605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awv267
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