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Unfolding of IgG domains detected by non-reducing SDS-PAGE

Monoclonal antibodies are very important in modern therapeutics and constitute a substantial percentage of newly approved drugs. Every therapeutic monoclonal antibody must be analyzed for structural and functional integrity, and all protein heterogeneities need to be identified and quantified. The c...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Kirley, Terence L., Norman, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095737/
https://ncbi.nlm.nih.gov/pubmed/29932917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.06.100
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