Llwytho...

An unfolded C(H)1 domain controls the assembly and secretion of IgG antibodies

A prerequisite for antibody secretion and function is the assembly into a defined quaternary structure, composed of two heavy and two light chains for IgG. Unassembled heavy chains are actively retained in the endoplasmic reticulum (ER) until they associate with light chains. Our mechanistic analysi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Feige, Matthias J., Groscurth, Sandra, Marcinowski, Moritz, Shimizu, Yuichiro, Kessler, Horst, Hendershot, Linda M., Buchner, Johannes
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908990/
https://ncbi.nlm.nih.gov/pubmed/19524537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.04.028
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