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Quality Control of Integral Membrane Proteins by Assembly-dependent Membrane Integration
Cell surface multi-protein complexes are synthesized in the endoplasmic reticulum (ER) where they undergo co-translational membrane integration and assembly. The quality control mechanisms that oversee these processes remain poorly understood. We show that less hydrophobic transmembrane (TM) regions...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770350/ https://ncbi.nlm.nih.gov/pubmed/23932713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.07.013 |
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