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Multi-domain unfolding of the Fab fragment of humanized anti-cocaine mAb characterized by non-reducing SDS-PAGE
Monoclonal antibodies and their fragments are widely used for research and therapy. Fab fragments are useful since they retain antigen binding specificity, but being smaller proteins, are better able to penetrate biological compartments and tumors, and do not induce Fc-dependent immunological system...
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| Publicado no: | Biochem Biophys Res Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7655625/ https://ncbi.nlm.nih.gov/pubmed/32988582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.09.051 |
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