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Multi-domain unfolding of the Fab fragment of humanized anti-cocaine mAb characterized by non-reducing SDS-PAGE

Monoclonal antibodies and their fragments are widely used for research and therapy. Fab fragments are useful since they retain antigen binding specificity, but being smaller proteins, are better able to penetrate biological compartments and tumors, and do not induce Fc-dependent immunological system...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochem Biophys Res Commun
Main Authors: Kirley, Terence L., Norman, Andrew B.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7655625/
https://ncbi.nlm.nih.gov/pubmed/32988582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.09.051
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