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Domain unfolding of monoclonal antibody fragments revealed by non-reducing SDS-PAGE

Monoclonal antibodies and derived fragments are used extensively both experimentally and therapeutically. Thorough characterization of such antibodies is necessary and includes assessment of their thermal and storage stabilities. Thus, assessment of the underlying conformational stabilities of the a...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Kirley, Terence L., Greis, Kenneth D., Norman, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218646/
https://ncbi.nlm.nih.gov/pubmed/30417132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2018.10.004
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