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Selective disulfide reduction for labeling and enhancement of Fab antibody fragments

Many methods have been developed for chemical labeling and enhancement of the properties of antibodies and their common fragments, including the Fab and F(ab’)(2) fragments. Somewhat selective reduction of some antibody disulfide bonds has been previously achieved, yielding antibodies and antibody f...

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Publicat a:Biochem Biophys Res Commun
Autors principals: Kirley, Terence L., Greis, Kenneth D., Norman, Andrew B.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362313/
https://ncbi.nlm.nih.gov/pubmed/27983990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.10.128
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