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Selective disulfide reduction for labeling and enhancement of Fab antibody fragments

Many methods have been developed for chemical labeling and enhancement of the properties of antibodies and their common fragments, including the Fab and F(ab’)(2) fragments. Somewhat selective reduction of some antibody disulfide bonds has been previously achieved, yielding antibodies and antibody f...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Kirley, Terence L., Greis, Kenneth D., Norman, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362313/
https://ncbi.nlm.nih.gov/pubmed/27983990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.10.128
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