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Selective disulfide reduction for labeling and enhancement of Fab antibody fragments

Many methods have been developed for chemical labeling and enhancement of the properties of antibodies and their common fragments, including the Fab and F(ab’)(2) fragments. Somewhat selective reduction of some antibody disulfide bonds has been previously achieved, yielding antibodies and antibody f...

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Foilsithe in:Biochem Biophys Res Commun
Main Authors: Kirley, Terence L., Greis, Kenneth D., Norman, Andrew B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362313/
https://ncbi.nlm.nih.gov/pubmed/27983990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.10.128
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