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Selective disulfide reduction for labeling and enhancement of Fab antibody fragments

Many methods have been developed for chemical labeling and enhancement of the properties of antibodies and their common fragments, including the Fab and F(ab’)(2) fragments. Somewhat selective reduction of some antibody disulfide bonds has been previously achieved, yielding antibodies and antibody f...

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Publicado en:Biochem Biophys Res Commun
Autores principales: Kirley, Terence L., Greis, Kenneth D., Norman, Andrew B.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5362313/
https://ncbi.nlm.nih.gov/pubmed/27983990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.10.128
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