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Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate-induced apoptosis

The present study assessed the antitumor effect of artesunate (ART) in vitro and in vivo, as well as its underlying mechanism of action in HCT116 colon cancer cells. An MTT assay, DAPI staining, flow cytometry, western blotting, immunohistochemistry, transmission electron microscopy and TUNEL assay...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Med
Hoofdauteurs: Jiang, Feng, Zhou, Jin-Yong, Zhang, Dan, Liu, Ming-Hao, Chen, Yu-Gen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: D.A. Spandidos 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089754/
https://ncbi.nlm.nih.gov/pubmed/29901098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3712
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