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Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate-induced apoptosis

The present study assessed the antitumor effect of artesunate (ART) in vitro and in vivo, as well as its underlying mechanism of action in HCT116 colon cancer cells. An MTT assay, DAPI staining, flow cytometry, western blotting, immunohistochemistry, transmission electron microscopy and TUNEL assay...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Int J Mol Med
Päätekijät: Jiang, Feng, Zhou, Jin-Yong, Zhang, Dan, Liu, Ming-Hao, Chen, Yu-Gen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: D.A. Spandidos 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089754/
https://ncbi.nlm.nih.gov/pubmed/29901098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3712
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