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Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate-induced apoptosis

The present study assessed the antitumor effect of artesunate (ART) in vitro and in vivo, as well as its underlying mechanism of action in HCT116 colon cancer cells. An MTT assay, DAPI staining, flow cytometry, western blotting, immunohistochemistry, transmission electron microscopy and TUNEL assay...

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Detalhes bibliográficos
Publicado no:Int J Mol Med
Main Authors: Jiang, Feng, Zhou, Jin-Yong, Zhang, Dan, Liu, Ming-Hao, Chen, Yu-Gen
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089754/
https://ncbi.nlm.nih.gov/pubmed/29901098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2018.3712
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