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Inhibition of autophagy enhances apoptosis induced by bortezomib in AML cells

Bortezomib is a novel proteasome inhibitor, which has been successfully used to treat mantle cell lymphoma and multiple myeloma. However, the direct effects of bortezomib on acute promyelocytic leukaemia (APL) have not been fully investigated. In the present study, the WST-8 assay, western blotting,...

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Bibliografske podrobnosti
izdano v:Oncol Lett
Main Authors: Jiang, Lei, Zhao, Yi-Ming, Yang, Ming-Zhen
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751351/
https://ncbi.nlm.nih.gov/pubmed/33376542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.12370
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